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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM59A All Species: 11.52
Human Site: S484 Identified Species: 36.19
UniProt: Q9H706 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H706 NP_073588.1 876 97186 S484 R C D Q F R G S V R S K C A T
Chimpanzee Pan troglodytes XP_524002 932 103068 S541 R C D Q F R G S V R S K C A T
Rhesus Macaque Macaca mulatta XP_001103392 618 69796 E248 Y D L H F I R E G H R Y K F V
Dog Lupus familis XP_547618 865 96077 S474 R C D P S R G S V R S K C A T
Cat Felis silvestris
Mouse Mus musculus Q3UFT3 876 97249 S484 R C D T L R G S T R S T C A P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509268 641 69426 E271 A V T K K R M E R V G G R V K
Chicken Gallus gallus
Frog Xenopus laevis Q6NRE4 876 97412 R482 K N K C D S F R G S L P S R C
Zebra Danio Brachydanio rerio Q7ZVU1 867 95774 L479 V K N A G P V L D H N E G V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.8 62.6 90.4 N.A. 91.3 N.A. N.A. 32.6 N.A. 78 63.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 93.4 66 93.2 N.A. 95 N.A. N.A. 45.4 N.A. 85.3 73.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 66.6 N.A. N.A. 6.6 N.A. 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 86.6 N.A. 66.6 N.A. N.A. 13.3 N.A. 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 13 0 0 0 0 0 0 0 0 0 50 0 % A
% Cys: 0 50 0 13 0 0 0 0 0 0 0 0 50 0 13 % C
% Asp: 0 13 50 0 13 0 0 0 13 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 25 0 0 0 13 0 0 0 % E
% Phe: 0 0 0 0 38 0 13 0 0 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 13 0 50 0 25 0 13 13 13 0 0 % G
% His: 0 0 0 13 0 0 0 0 0 25 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % I
% Lys: 13 13 13 13 13 0 0 0 0 0 0 38 13 0 13 % K
% Leu: 0 0 13 0 13 0 0 13 0 0 13 0 0 0 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 13 0 0 0 0 0 0 0 13 0 0 0 0 % N
% Pro: 0 0 0 13 0 13 0 0 0 0 0 13 0 0 13 % P
% Gln: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 50 0 0 0 0 63 13 13 13 50 13 0 13 13 13 % R
% Ser: 0 0 0 0 13 13 0 50 0 13 50 0 13 0 0 % S
% Thr: 0 0 13 13 0 0 0 0 13 0 0 13 0 0 38 % T
% Val: 13 13 0 0 0 0 13 0 38 13 0 0 0 25 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _